Claritop
Description:
Claritop
(Clarithromycin) is a semi-synthetic derivative of Erythromycin A. It
exerts its anti bacterial action by binding to the 50s ribosomal
sub-unit of susceptible bacteria and suppresses protein synthesis. It is
highly potent against a wide variety of aerobic and anaerobic
gram-positive and gram negative organisms . The minimum inhibitory
concentrations (MICs) of Clarithromycin are generally two-fold lower
than the MICs of Erythromycin . The 14-hydroxy metabolite of
clarithromycin also has anti-microbial activity. The MICs of this
metabolite are equal or two-fold higher than the MICs of the parent
compound , except for H.influenzae where the 14-hydroxy metabolite is
two-fold more active than the parent compound .
Presentations :
Claritop –250mg Film Coated Tablets : Each F/C tablet contains 250mg Clarithromycin in blisters pack of 14 tablets .
Claritop –500mg film coated tablets : Each F/C tablet contains 500mg Clarithromycin in blister packs of 20,14 tablets .
Claritop Suspension : Each 5 ml contains 125mg Clarithromycin in 60& 100ml bottle .
Hospital packs of different sizes are also available.
Some presentation may not be available in certain countries.
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